Kevin Jacobs joined the faculty at the University of Miami in 2004. He completed his Masters in applied exercise physiology at San Diego State University in 1993 and worked as a research physiologist at the Naval Health Research Center in San Diego until 1995. He earned his Ph.D. in exercise physiology from The Ohio State University in 2000 and completed a four-year postdoctoral fellowship at the University of California, Berkeley and the Palo Alto VA Health Care System.
His research focus is human metabolism and more specifically the ways in which factors such as exercise intensity, nutritional status, training status, gender, age, menstrual cycle phase, and environment alter substrate (carbohydrate, fat, and protein) use at rest and during exercise. His research involves basic measurements such as the analysis of respiratory gas exchange and concentrations of various blood metabolites and hormones to more complex measurements of substrate turnover by stable isotope infusion and analysis. The results of his research not only further basic science, but are also applied to improving our understanding of the etiology of metabolic diseases such as obesity and non-insulin-dependent diabetes and developing more effective lifestyle interventions to prevent and treat these diseases. His research has involved men and women of various ages and levels of fitness as subjects that have been studied in environments as varied as a standard laboratory at sea level to a high altitude research station at Pikes Peak, Colorado (14,100 ft. elevation).
While at the University of Miami, Dr. Jacobs and his students have investigated many topics including pharmacological and ischemic preconditioning effects on cardiovascular hemodynamics and exercise performance at simulated moderate and high altitudes, pre-exercise sprints and glycemic control in type 1 diabetics during prolonged exercise, cervical strength training and head kinematics during a football tackle, and aerobic training and markers inflammation. Additionally, Dr. Jacobs is engaged in collaborative research with The Miami Project to Cure Paralysis at the University of Miami Miller School of Medicine to examine the effects of exercise and nutritional manipulations on lipid use in men and women with spinal cord injuries.
He is a member of the American College of Sports Medicine. His most recent publications include “Ischemic preconditioning does not improve peak exercise capacity at sea level or simulated high altitude in trained male cyclists” in Applied Physiology, Nutrition, and Metabolism, Heavy reliance on carbohydrate across a wide range of exercise intensities during voluntary arm ergometry in persons with paraplegia” in Journal of Spinal Cord Medicine, “Sildenafil has little influence on cardiovascular hemodynamics or 6-km time trial performance in trained men or women at simulated high altitude” in High Altitude Medicine and Biology, and “Sildenafil does not improve steady state cardiovascular hemodynamics, peak power, or 15-km time trial cycling performance at simulated moderate or high altitudes in men and women” in European Journal of Applied Physiology.
View Curriculum Vitae
Sherman WM, Jacobs KA, and Ferrara C. Nutritional strategies to optimize athletic performance. In: Handbook of Exercise in Diabetes. Ruderman N, Devlin JT, and Schneider SH (Eds.). Alexandria: American Diabetes Association, 2002, pp. 339-354.
Jacobs KA, Paul DR, and Sherman WM. Fat metabolism. In: Exercise and Sport Science. Garrett, Jr. WE and Kirkendall DT (Eds.). New York: Lippincott Williams & Wilkins, 1999, pp. 9-18.
Sherman W, Jacobs K, and Leenders N. Carbohydrate metabolism during endurance exercise. In: Overtraining In Sport: Physiological, Psychological, and Biomedical Considerations. Kreider RB, Fry AC, and O’Toole ML (Eds.). Champaign: Human Kinetics, 1998, pp. 289-307.
Juried or refereed journal articles and exhibitions
Vance DD, Chen GL, Stoutenberg M, Myerburg RJ, Jacobs K, Nathanson L, Perry A, Seo D, Goldschmidt-Clermont PJ, Rampersaud E. Cardiac performance, biomarkers and gene expression studies in previously sedentary men participating in half marathon training. BMC Sports Science, Medicine, and Rehabilitation, 19, Epub ahead of print, 2014.
Jacobs KA, Burns P, Kressler J, and Nash MS. Heavy reliance on carbohydrate across a wide range of exercise intensities during voluntary arm ergometry in persons with paraplegia. Journal of Spinal Cord Medicine 36: 427-435, 2013.
Kressler J, Jacobs KA, Burns P, Betancourt L, Nash MS. Effect of circuit resistance training and timely protein supplementation on exercise-induced fat oxidation in tetraplegic adults. Topics in Spinal Cord Injury Rehabilitation, In Press, 2013.
Lisman P, Signorile JF, Del Rossi G, Asfour S, Eltoukhy M, Stambolian D, and Jacobs KA. Investigation of the effects of cervical strength training on neck strength, EMG, and head kinematics during a football tackle. International Journal of Sports Science and Engineering, 6: 131-140, 2012.
Stoutenberg M, Kressler J, Chen GL, Perry AC, Meyerburg RJ, Mendez AJ, Signorile JF, Arheart KL, Lewis JE, Jacobs KA. Aerobic training does not alter CRP concentrations in apparently healthy, untrained men. Journal of Sports Medicine and Physical Fitness 52: 53-62, 2012.
Jacobs KA, Kressler J, Stoutenberg M, Roos BA, Friedlander AL. Sildenafil has little influence on cardiovascular hemodynamics or 6-km time trial performance in trained men or women at simulated high altitude. High Altitude Medicine and Biology 12: 215-222, 2011.
Kressler J, Stoutenberg M, Roos BA, Friedlander AL, Perry AC, Signorile JF, Jacobs KA. Sildenafil does not improve steady state cardiovascular hemodynamics, peak power, or 15-km time trial cycling performance at simulated moderate or high altitudes in men and women. European Journal of Applied Physiology 111: 3031-3040, 2011.
Musto A, Jacobs K, Nash M, Del Rossi G, and Perry A. The effects of an incremental approach to 10,000 steps a day on metabolic syndrome components in sedentary overweight women. Journal of Physical Activity and Health 7: 737-745, 2010.
Adams JA, Edwards D, Serravite D, Bedient AM, Huntsman E, Jacobs KA, Del Rossi G, Roos BA, and Signorile JF. Journal of Strength and Conditioning Research 23: 237-245, 2009.
Suh SH, Paik IY, and Jacobs KA. Regulation of blood glucose homeostasis during exercise. Molecules and Cells 23: 272-279, 2007.
Wallis GA, Friedlander AL, Jacobs KA, Horning MA, Fattor JA, Wolfel EE, Lopaschuk GD, and Brooks GA. Substantial working muscle glycerol turnover during two-legged cycle ergometry. American Journal of Physiology - Endocrinology and Metabolism 293: E950-E957, 2007.
Friedlander AL, Jacobs KA, Fattor JA, Horning MA, Hagobian TA, Bauer TA, Wolfel EE, and Brooks GA. Contributions of working muscle to whole body lipid metabolism are altered by exercise intensity and training. American Journal of Physiology - Endocrinology and Metabolism 292: E107-E116, 2006.
Hagobian TA, Jacobs KA, Subudhi AW, Fattor JA, Rock PB, Muza SR, Fulco CS, Braun B, Grediagin A, Mazzeo RS, Cymerman A, and Friedlander AL. Cytokine response at high altitude: effects of exercise and antioxidants at 4,300 m. Medicine and Science in Sports and Exercise 38: 276-285, 2006.
Jacobs KA, Krauss RM, Fattor JA, Horning MA, Friedlander AL, Bauer TA, Hagobian TA, Wolfel EE, and Brooks GA. Endurance training has little effect on active muscle fatty acid, lipoprotein cholesterol, or triglyceride net balances. American Journal of Physiology - Endocrinology and Metabolism 291: E656-E665, 2006.
Subudhi AW, Jacobs KA, Hagobian TA, Fattor JA, Muza SR, Fulco CS, Cymerman A, and Friedlander AL. Changes in ventilatory threshold at high altitude: effect of antioxidants. Medicine and Science in Sports and Exercise 38: 1425-1431, 2006.
Fattor JA, Miller BF, Jacobs KA, and Brooks GA. Catecholamine response is attenuated during moderate intensity exercise in response to the “lactate clamp”. American Journal of Physiology - Endocrinology and Metabolism 288: E143-147, 2005.
Hsu AR, Hagobian TA, Jacobs KA, Attallah H, and Friedlander AL. Effects of heat removal through the hand on metabolism and performance during cycling in the heat. Canadian Journal of Applied Physiology 30: 87-104, 2005.
Jacobs KA, Casazza GA, Suh SH, Horning MA, and Brooks GA. Fatty acid re-esterification but not oxidation is increased by oral contraceptive use. Journal of Applied Physiology 98: 1720-1731, 2005.
Miller BF, Lindinger MI, Fattor JA, Jacobs KA, LeBlanc PJ, Duong M, Heigenhauser GJF, and Brooks GA. Hematological and acid-base changes in men during prolonged exercise with and without sodium-lactate infusion. Journal of Applied Physiology 98: 856-865, 2005.
Casazza GA, Jacobs KA, Suh SH, Miller BF, Horning MA, and Brooks GA. Menstrual cycle phase and oral contraceptive effects on triglyceride mobilization during exercise. Journal of Applied Physiology 97: 302-309, 2004.
Hagobian TA, Jacobs KA, Kiratli BJ, and Friedlander AL. Foot cooling reduces exercise-induced hyperthermia in men with spinal cord injury. Medicine and Science in Sports and Exercise 36: 411-417, 2004.
Jacobs KA, Paul DR, Geor RJ, Hinchcliff KW, Sams RA, and Sherman WM. Dietary composition influences short-term endurance training-induced adaptations of substrate partitioning during exercise. International Journal of Sport Nutrition and Exercise Metabolism 14: 38-61, 2004.
Subudhi AW, Jacobs KA, Hagobian TA, Fattor JA, Fulco CS, Muza SR, Rock PB, Hoffman AR, Cymerman A, and Friedlander AL. Antioxidant supplementation does not attenuate oxidative stress at high altitude. Aviation, Space, and Environmental Medicine 75: 881-888, 2004.
Paul DR, Jacobs KA, Geor RJ, Hinchcliff KW, and Lamb DR. No effect of pre-exercise meal on substrate metabolism and time trial performance during intense exercise. International Journal of Sport Nutrition and Exercise Metabolism 13: 489-503, 2003.
Miller BF, Fattor JA, Jacobs KA, Horning MA, Suh SH, Navazio F, and Brooks GA. Metabolic and cardiorespiratory responses to “the lactate clamp". American Journal of Physiology - Endocrinology and Metabolism 283: E889-E898, 2002.
Miller BF, Fattor JA, Jacobs KA, Horning MA, Navazio F, Lindinger MI, and Brooks GA. Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion. Journal of Physiology 544: 963-975, 2002.
Paul DR, Mulroy SM, Horner JA, Jacobs KA, and Lamb DR. Carbohydrate-loading during the follicular phase of the menstrual cycle: effects on muscle glycogen and exercise performance. International Journal of Sport Nutrition and Exercise Metabolism 11: 430-442, 2001.
Jacobs KA, and Sherman WM. The efficacy of carbohydrate supplementation and chronic high-carbohydrate diets for improving endurance performance. International Journal of Sport Nutrition 9: 92-115, 1999.
Jacobs K, Nichols J, Holmes B, and Buono M. Isometric cervical extension strength of recreational and experienced cyclists. Canadian Journal of Applied Physiology 20:230-239, 1995.